TIA1 antibody

Catalog No. ABIN5704065

This anti-TIA1 antibody is a Rabbit Polyclonal antibody detecting TIA1 in WB, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for TIA1 antibody (ABIN5704065)

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-TIA1 Antibody

Purpose: TIA1 antibody

Immunogen: TIA1 cytotoxic granule-associated RNA binding protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TIA1

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Alternative Name: TIA1

Background:

Synonyms: Cytotoxic granule associated RNA binding protein TIA1|Nucleolysin TIA-1 isoform p40|RNA-binding protein TIA-1|T-cell-restricted intracellular antigen-1 (TIA-1)|p40-TIA-1|TIA1

Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Gene ID: 7072

UniProt: P31483